Departments

HOME › Departments › Biomedical Chemistry

Biomedical Chemistry

Our major research interests include virulence mechanisms and metabolism of protozoa, particularly Plasmodium spp. causing malaria and Entamoeba histolytica causing amebic dysentery. We mainly focus on vesicular trafficking, phagocytosis, autophagy, proteases, amino acid metabolisms, RNA maturation, translation, drug development, and organellogenesis. Our research approaches are very robust, and include biochemistry, molecular and cell biology, live imaging, multi-omics including metabolomics, and reverse genetics. We always have several foreign students and guest researchers. We welcome you to our laboratory, full of international atmosphere.

Major projects

1. Molecular elucidation of pathogenesis of parasites
2. Biochemical and biological analyses of metabolism and organelles unique to parasites
3. Analysis of vesicular traffic, protein secretion, and phagocytosis/trogocytosis in parasites
4. Genome wide analysis and comparison of parasite strains
5. Drug discovery and development against protozoan infections such as malaria and amebiasis
6. Elucidation of divergence of RNA maturation and translation


Course Description

Special Lecture in Biomedical Chemistry I (2 credits)
Special Lecture in Biomedical Chemistry II (2 credits)

Professor Nozaki and Staff

All the classes will be given as either a lecture or paper reading. Topics include virulence mechanisms and metabolism of parasitic protozoa, such as Plasmodium spp. causing malaria, and Entamoeba histolytica causing amebic dysentery.

Special Lecture in Tropical Infectious Diseases I (2 credits)
Special Lecture in Tropical Infectious Diseases II (2 credits)

Professor Nozaki and Staff

The lectures about various topics, especially parasitology, in tropical medicine will be given by experts.


Teaching Staff

Tomoyoshi NOZAKI: Professor, since 2017
M.D., Ph.D., Keio University, 1997

1988 JICA expert at Recife, Brazil
1989-1992 Post-doctral fellow at Laboratory of Parasitic Diseases, NIAID, NIH
1992-1995 Research Associate at the Rockefeller University
1996-1999 Assistant Professor at Department of Tropical Medicine and Parasitology, Keio University School of Medicine
1999-2004 Laboratory Head, Laboratory of Molecular Parasitology, Department of Parasitology, National Institute of Infectious Diseases
2001-2004 Investigator, PRESTO, JST
2005-2008 Professor, Department of Parasitology, Gunma University Graduate School of Medicine
2008-2017 Director, Department of Parasitology, National Institute of Infectious Diseases
2009-2017 Professor, Graduate School of Life and Environmental Sciences, University of Tsukuba

Yoh-ichi WATANABE: Associate Professor, since 2007
B.Eng., Faculty of Engineering, The University of Tokyo, 1988
M.Eng., Graduate School of Engineering, The University of Tokyo, 1990
Ph.D., The University of Tokyo, 1994

JSPS Research Fellow, The University of Tokyo, 1993-1994
Granted Researcher of JICA, Institute for Medical Research, Malaysia, 1994-1995
Research Associate of Parasitology, Institute of Medical Sciences, The University of Tokyo, 1995-1996
NEDO Postdoctoral Fellow, The University of Tokyo, 1996
Postdoctoral Fellow, Faculty of Medicine, Dalhousie University, Canada, 1996-2000
Research Associate, Graduate School of Medicine, The University of Tokyo, 2000-2001
Lecturer, Graduate School of Medicine, The University of Tokyo, 2001-2007

Ghulam, Jeelani: Assistant Professor, since 2017
B. Sci., Faculty of Science, Aligarh Muslim University, India, 2003
M. Sci., Faculty of Science, Hamdard University, India, 2005
Ph.D., Faculty of Medicine, Keio University, 2013

Research Assistant, Department of Biochemistry, Faculty of Life Sciences, Aligarh Muslim University, India, 2005-2007
Instructor, Global center of excellence (G-COE) for Human Metabolomic Systems Biology, Keio University, 2007-2012
Special appointed Researcher, Department of Parasitology, National Institute of Infectious Diseases, 2012-2013
Research Scientist, Department of Parasitology, National Institute of Infectious Diseases, 2013-2015
Resident Researcher, Japan Agency For Medical Research And Development (AMED), 2015-2017

Santos, Herbert: Assistant Professor, since 2018
B. Sci., University of the Philippines Manila, Philippines, 2003
M. Sci., University of the Philippines Diliman, Philippines, 2009
Ph.D., University of Tsukub, 2015

Teacher, Basic Education Department, San Beda University, Manila, Philippines, 2003-2004
Instructor, School of Biological Engineering, Chemical Engineering, and Chemistry, Mapua University, Manila, Philippines, 2004-2008
Instructor, Institute of Biology, College of Science, University of the Philippines Diliman, Quezon City, Philippines, 2008-2010
Assistant Lecturer, Department of Biology, College of Arts and Sciences, Miriam College, Quezon City, Philippines, 2010-2015
Postdoctoral Researcher, Graduate School of Life and Environmental Sciences, University of Tsukuba, 2015-2016
Research Scientist, Department of Parasitology, National Institute of Infectious Diseases, 2016-2018


Department Website : Biomedical Chemistry

International Social Medicine
International Biomedical Sciences
Associated Departments